Influence of catechins on bystander responses in CHO cells induced by alpha-particle irradiation.
نویسندگان
چکیده
In this work, we studied alpha-particle induced and medium-mediated bystander effects in Chinese hamster ovary (CHO) cells through micronucleus (MN) assay. We showed that signal transduction from irradiated cells to bystander cells occur within a short time after irradiation. We then studied the effects of ROS (reactive oxygen species)-scavenging catechins in the medium before irradiation. We observed decreases in the percentage of bystander cells with MN formation and thus proved the protection effect of catechins on bystander cells from radiation.
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ورودعنوان ژورنال:
- Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
دوره 68 4-5 شماره
صفحات -
تاریخ انتشار 2010